For the treatment of flea and tick infestations in dogs when the concurrent prevention of heartworm disease (Dirofilaria immitis larvae), angiostrongylosis (reduction in level of immature adults (L5) and adults of Angiostrongylus vasorum), thelaziosis (adult Thelazia callipaeda) and/or treatment of gastrointestinal nematode infestations is indicated
It should be administered at a dose of 2.50–5.36 mg/kg of Afoxolaner and 0.50–1.07 mg/kg of Milbemycin oxime