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Companion animals | Pain Treatment & Management

HeartClear S/M/L
Ivermectin & Pyrantel Tablet

What is HeartClear S/M/L?
Heartclear chewable tablets provides protection against heartworms, and treats and controls roundworms and hookworms.


  • Effectively prevents heartworms
  • Treats and controls roundworms & hookworms
  • Only given once a month
  • Delicious flavor makes them easy to administer

How it Works:

Heartclear Chewables contains ivermectin, a broad-spectrum antiparasitic medication used to prevent heartworms. Ivermectin kills by interfering with nervous system and muscle function, in particular by enhancing inhibitory neurotransmission. Second active ingredient Pyrantel Pamoate, an anthelminthic, used to prevent roundworms and hookworms. Pyrantel pamoate acts as a depolarizing neuromuscular blocking agent, thereby causing sudden contraction, followed by paralysis, of the helminths.

Cautions when giving Heartclear Chewable Tablets:

  • It may cause sensitivities in herding dog breeds.
  • They should be chewed, not swallowed whole.
  • Make sure that your dog eats the entire dose. It is important to give your dog Heartclear Chewables every month year-round.
  • If you miss than two months of dosage, please consult with your veterinarian as to whether to continue medication.

What happens if I miss giving a dose ?
Give the missed dose as soon as you remember. Do not give a double dose of the medication.

What should I do if an accidental overdose ?
Seek emergency veterinary medical treatment.

What should I avoid while giving Heartclear Chewables to my pet?
Because humans can contract hookworm from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.

What are the possible side effects of Heartclear Chewables?
Side effects of Heartclear Chewable tablets are rare at the recommended heartworm prevention dose. Higher doses in dogs may cause tremors, dilated pupils, loss of body weight and death.


  • Give Heartclear Chewables once a month on the same day of each month year round.
  • Heartclear Chewables are for dogs only. Do not give to cats.
  • Heartclear Chewables should not be swallowed whole.
  • Chewables may be broken and fed to dogs as pieces, or crumbled and mixed with food.
  • Watch dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.


  • Heartclear chewables should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

  • Dog weight (kg) Chewable tablet / month Ivermectin (content) Pyrantel(content)
    Upto 11 1 68 mcg 57 mg
    12 to 22 1 136 mcg 114 mg
    23 to 45 1 272 mcg 227 mg

  • For dogs over 45kg use the appropriate combination of these Chewable Tablets.

For Small Dogs : (Upto 11 Kg)

Active Ingredient Amount
Ivermectin 68 mcg
Pyrantel Pamoate equivalent to Pyrantel 57 mg

For Medium Dogs : ( From 12 Kg to 22 Kg)

Active Ingredient Amount
Ivermectin 136 mcg
Pyrantel Pamoate equivalent to Pyrantel 114 mg

For Large Dogs : (from 23 Kg to 45 Kg)

Active Ingredient Amount
Ivermectin 272 mcg
Pyrantel Pamoate equivalent to Pyrantel 227 mg